Pigmented lesions can be classified into epidermal, dermal, and mixed depending on where the pigment is located in the skin. DEKA has developed specific systems for different wavelengths and pulse durations that can be used according to the lesion: we can selectively target and destroy melanin in pigmented areas. In mixed lesions, it is advisable to treat the epidermal component first and then, once this has been attenuated, penetrate deeper into the dermal component with the laser.